Quarterly report pursuant to Section 13 or 15(d)

Organization and Description of Business - Additional Information (Detail)

v3.22.2.2
Organization and Description of Business - Additional Information (Detail)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Mar. 31, 2022
USD ($)
Sep. 30, 2021
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Sep. 30, 2022
USD ($)
segment
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
Class of Stock [Line Items]                  
Number of operating segments | segment             1    
Net loss $ (24,505) $ (27,094) $ (27,769) $ (22,682) $ (23,222) $ (17,551) $ (79,368) $ (63,455)  
Cash flows from operating activities             (65,324) $ (55,188)  
Accumulated deficit (846,224)           (846,224)   $ (766,856)
Cash and cash equivalents and marketable securities $ 153,400           $ 153,400