As of March 31, 2022, there were 2,433,522 shares available for future grants under the Company’s 2013 Equity Incentive Plan and no shares available for grant under the Company’s 2020 New Hire Plan. On January 1, 2022, in accordance with the annual share increase provision in the 2013 Plan, the Company added 4,233,896 shares to the 2013 Plan share reserve. During the three months ended March 31, 2022, the Company granted 3,479,668 stock options, which primarily related to its option grants issued to employees and directors.