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Corporate Presentation |
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Seladelpar Improved the Lipid Profile of Patients With Primary Biliary Cholangitis (PBC): Results From Phase 2 and 3 Clinical Studies |
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Seladelpar, a PPAR-delta agonist, improves inflammatory lipid mediators in the serum metabolome in patients with primary biliary cholangitis (PBC) |
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Effects of single and multiple doses of the selective PPARĪ“ agonist seladelpar on diurnal markers of bile acid synthesis in mice |
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The selective PPAR-delta agonist seladelpar (MBX-8025) suppresses bile acid synthesis by reducing hepatocyte CYP7A1 through the FGF21 pathway |