Quarterly report pursuant to Section 13 or 15(d)

Organization and Description of Business - Additional Information (Detail)

v3.7.0.1
Organization and Description of Business - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jul. 24, 2017
Feb. 07, 2017
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Organization And Description Of Business [Line Items]              
Net loss     $ (8,929) $ (6,992) $ (14,280) $ (13,840)  
Cash flows from operating activities         (8,094) $ (12,210)  
Accumulated deficit     (437,239)   (437,239)   $ (422,959)
Cash and cash equivalents and marketable securities     $ 16,700   $ 16,700    
Net proceeds from public offering   $ 9,200          
Subsequent Event [Member]              
Organization And Description Of Business [Line Items]              
Net proceeds from public offering $ 91,100