Annual report pursuant to Section 13 and 15(d)

Organization and Description of Business - Additional Information (Detail)

v3.3.1.900
Organization and Description of Business - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Organization, Consolidation and Presentation of Financial Statements [Abstract]    
Net loss $ (15,529) $ (31,917)
Cash flows from operating activities (23,324) (21,114)
Accumulated deficit (396,288) $ (380,759)
Cash and cash equivalents and marketable securities $ 41,500